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Editorial #PunktZwrotny2050 Sources checked: 09.09.2026 How to read this data
  1. 2026
    These ObservationsChineseN = 362

    Three-year efficacy and safety of repeated low-level red-light therapy for myopia control: a multicentre real-world study

    Yanping Chen; Wei Wang; Ruilin Xiong; Fang Yu; Shaoxin Pan; Jing Dong; Jian Zhang; Zhuoting Zhu; Xiaohu Ding; Bin Wang; Yanxian Chen; Henry Ho-lung Chan; Kai Yip Choi; Sonia Seen Hang Chan; Yingfeng Zheng; Danli Shi; Yuri Aung; Shoji Kishi; Kyoko Ohno-Matsui; Mingguang He

    10.1136/bjo-2025-328687

    The real-world study includes groups with varying durations of RLRL use, including 91 participants treated with 3 for at least one year.

    These are groups by length of treatment, not a three-year RCT. Possible selection of continuators. Median in the longest group 3,65 of the year.

  2. 2026
    RCTSpainN = 26

    Repeated low-level red-light therapy combined with orthokeratology for myopia control in Spain: a randomised controlled study

    María José Fernández Fidalgo; Victoria D Ferigo Ferrel; Yue Wu; Ziyi Qi; Yuri Yin-Moe Aung; Yanxian Chen; Zhuoting Zhu; Fernando J Fernández-Velázquez

    10.1136/bjo-2025-328347

    A Spanish RCT showed greater axis control when RLRL was added to orthokeratology than with orthokeratology alone.

    Small, single-center and unblinded trial. This is a combination treatment study, not a European monotherapy RCT RLRL .

  3. 2026
    ObservationChineseN: nie dotyczy/nieustalone

    Five-year efficacy and safety of repeated low-level red light therapy for myopia control in children: a multicenter, real-world study

    Juzhao Zhang; Jun Yu; Haidong Zou; Yan Xu

    10.1016/j.aopr.2026.06.002

    The 2026 publication by Zhang et al. describes multicenter real-world data with follow-up dating back to 5 years.

    DOI, authors and publication type were verified. Follow-up for 5 years does not mean that each participant was followed for 5 years; this is not a five-year RCT.

  4. 2026
    Pilot RCT Australia N = 34

    Efficacy of repeated red-light laser therapy for myopia control in Australian children: a pilot randomised controlled trial

    Gabriella Bulloch; Ziyi Qi; Yuri Yin-Moe Aung; Zeinab Fakih; Diba Rezazadeh; Dzung Tran; Zhuoting Zhu; Nelofar Deen

    10.1080/08164622.2026.2648328

    The Australian pilot RCT showed less axis gain in the RLRL group; extends data beyond Chinese populations.

    34 children, three withdrawals in the RLRL group, including one due to headache. It does not confirm equal effectiveness in all populations.

  5. 2026
    Cross-sectional studyChinaN = 66

    Safety analysis of repeated low-level red light therapy on cone mosaic and microvasculature by adaptive optics scanning laser ophthalmoscopy

    Yu Yue; Ni Zhang; Ke-Yu Liu; Yuan-Yuan Zhong; Han Wang; Shu-Lin Liu; Wen-Juan Wan; Yan-Lai Zhang; Wen-Li Deng

    10.1016/j.pdpdt.2026.105473

    The AOSLO study showed no significant loss of cone density or differences in microcirculatory parameters tested after at least 8 months of RLRL.

    66 eyes, of which 20 in the RLRL group; the unit is the eye, not the number of patients. Cross-sectional examination does not exclude rare or distant lesions.

  6. 2026
    Official source Poland N: not applicable / undetermined

    UD148 — projekt zmiany opieki zdrowotnej nad uczniami

    Public institution identified in the source

    https://www.gov.pl/web/premier/projekt-ustawy-o-zmianie-ustawy-o-opiece-zdrowotnej-nad-uczniami

    The Chancellery of the Prime Minister describes the project of changes in the organization of health care for students and the problems of its availability.

    The status of the project was checked on the website of the Chancellery of the Prime Minister. We do not present the proposed solutions as a valid reform.

  7. 2026
    Official source Poland N: not applicable / undetermined

    NIK — niewystarczająca opieka zdrowotna w szkołach

    Najwyższa Izba Kontroli

    https://www.nik.gov.pl/aktualnosci/sprawy-spoleczne/niewystarczajaca-opieka-zdrowotna-w-szkolach.html

    The Supreme Audit Office audit identified organizational problems and problems with further proceedings after incorrect school test results.

    Regional control; does not allow determining the percentage of irregularities for the entire country.

  8. 2026
    Official source Poland N: not applicable / undetermined

    Opinia AOTMiT — program wad wzroku i słuchu w gminie Żary

    Agencja Oceny Technologii Medycznych i Taryfikacji

    https://www.aotm.gov.pl/aktualnosci/najnowsze/opinia-prezesa-program-profilaktyki-i-wczesnego-wykrywania-wad-wzroku-i-sluchu-wsrod-dzieci-wczesnoszkolnych-w-gminie-zary-na-lata-2026-2030/

    AOTMiT publishes an opinion on the local program for the prevention of vision and hearing defects in the Żary commune for the years 2026–2030.

    The opinion about the project does not confirm its actual scope or implementation results.

  9. 2026
    Scientific commentaryEuropeN: not applicable / not determined

    Myopia Trends in Europe: A Reappraisal of Current Evidence

    Carla Lanca; Ian Morgan; Andrzej Grzybowski

    10.1007/s40123-026-01412-2

    Lance, Morgan and Grzybowski ( 2026 ) point out that global extrapolations may overestimate the future burden of parts of European populations.

    Interpretive commentary, not a new national measurement and not proof that the myopia problem has disappeared.

  10. 2026
    Official source China N: not applicable / undetermined

    MOE — raportowany trend częstości miopii uczniów

    Public institution identified in the source

    https://www.moe.gov.cn/jyb_xwfb/s5147/202609/t20260904_1449012.html

    The September MOE announcement 2026 reports student myopia 49,9% in 2025 versus 53,6% in 2018.

    The administrative trend does not prove which policy component is responsible for the change. It is not a forecast for Poland.

  11. 2026
    Official source China N: not applicable / undetermined

    Plan pięciu obszarów zdrowia dzieci i młodzieży 2026–2030

    Ministerstwo Edukacji Chińskiej Republiki Ludowej

    https://www.moe.gov.cn/jyb_xxgk/moe_1777/moe_1779/202603/t20260324_1431885.html

    China's 2026–2030 plan outlines vision checks, electronic documentation and myopia targets by age.

    Objectives are target values, not achieved results. The document was signed 25.12.2025 ; The analyzed MOE publication comes from 2026.

  12. 2026
    Meta-analysis RCTGloballyN: not applicable/undetermined

    Efficacy and safety of low-concentration atropine combined with orthokeratology for children with myopia: a systematic review and meta-analysis of randomized controlled trials

    Xue-Qian Zhang; Ming Chen; Xi Duan; Ya-Nan Shao; Le-Huan Chen; Shi-Yu Liu; Xiao-Xue Zhan

    10.1186/s12886-026-04816-7

    A meta-analysis of RCTs showed additional inhibition of axis extension for low atropine with orthokeratology compared to orthokeratology alone.

    Differences in observation times and protocols; collective benefit does not imply indication for every combination.

  13. 2025
    Observational studyChinaN = 190

    Synergistic effect of defocus incorporated multiple segment glasses and repeated low level red light therapy against myopia progression

    Yan Yang; Shenghong Liu; Wenwen Gao; Lei Wang; Na Liu; Shiying Zhang; Lianjing Yang; Lingyun Cheng

    10.1038/s41598-024-81363-5

    In a retrospective analysis, DIMS + RLRL was associated with greater axis control than either method alone.

    Lack of randomization, unequal groups and no monofocal lens group. It does not establish a standard or ranking of all methods.

  14. 2025
    RCT crossoverChinaN: not applicable / undetermined

    Effect of Repeated Low-Level Red Light Versus 0.01% Topical Atropine on Myopia Progression: A Randomized Crossover-Controlled Trial

    Xuena Pang; Xuemin Jin; Aicun Fu; Weiqun Wang; Bingxin Zhao; Lili Shang; Minghang Chang; Nana Ma; Guangying Zheng

    10.1167/tvst.14.4.22

    The study compares RLRL with atropine 0,01% in a crossover design.

    It does not examine the simultaneous use of both methods. The choroidal parameters publication from DOI 10.1007 /s40123- 025-01169-0 describes the initial phase of the same study; We don't double the attempt.

  15. 2025
    Model / meta-analysisGloballyN = 5410945

    Global prevalence, trend and projection of myopia in children and adolescents from 1990 to 2050: a comprehensive systematic review and meta-analysis

    Jinghong Liang; Yingqi Pu; Jiaqi Chen; Meiling Liu; Bowen Ouyang; Zhengge Jin; Wenxin Ge; Zhuowen Wu; Xiuzhi Yang; Chunsong Qin; Cong Wang; Shan Huang; Nan Jiang; Lixin Hu; Yushan Zhang; Zhaohuan Gui; Xueya Pu; Shaoyi Huang; Yajun Chen

    10.1136/bjo-2024-325427

    Liang et al.'s model predicts 39,80% myopia in children and adolescents at 2050.

    276 studies from 50 countries; heterogeneous protocols. 2024 Online Publication, 2025 Journal Volume. Different population and model than Holden; these numbers should not be taken away as a trend change.

  16. 2025
    Official source Japan N: not applicable / undetermined

    MEXT — dane z badania krótkowzroczności uczniów

    MEXT, Japonia

    https://www.mext.go.jp/a_menu/kenko/hoken/mext_03197.html

    MEXT provides rules for access to individual student myopia data from fiscal years 2021–2023.

    Confirms the measurement design. It is not evidence of an equivalent to the Singapore NMPP.

  17. 2025
    Review / Consensus Global N: N/A / Undetermined

    IMI-Interventions for Controlling Myopia Onset and Progression 2025

    Mark A. Bullimore; Kathryn J. Saunders; Rigmor C. Baraas; David A. Berntsen; Zhi Chen; Audrey Wei Lin Chia; So Goto; Jun Jiang; Weizhong Lan; Nicola S. Logan; Raymond P. Najjar; Jan Roelof Polling; Scott A. Read; Emily C. Woodman-Pieterse; Noémi Széll; Pavan K. Verkicharla; Pei-Chang Wu; Xiaoying Zhu; James Loughman; Manbir Nagra; John R. Phillips; Huy D. M. Tran; Fuensanta A. Vera-Diaz; Jason Yam; Yue M. Liu; Sarah E. Singh; Christine F. Wildsoet

    10.1167/iovs.66.12.39

    IMI 2025 organizes optical, pharmacological, environmental and lighting strategies and the state of research on their effects.

    Mature technologies and emerging methods have a different evidence base. The inspection is not an individual clinical eligibility assessment of the child.

  18. 2025
    Meta-analysisEuropeN = 128012

    Prevalence of myopia in Europe: a systematic review and meta-analysis of data from 14 countries

    André Moreira-Rosário; Carla Lanca; Andrzej Grzybowski

    10.1016/j.lanepe.2025.101319

    The European meta-analysis obtained 23,5% cumulative frequency; 18,9% in studies with cycloplegia and 31,2% without it.

    22 test, I²= 99,7% . This is not a percentage for Poland or an adjustment that can be applied to every study. When stratified by age and cycloplegia, the increase was less clear.

  19. 2025
    Systematic review Global N = 17509

    Interventions for myopia control in children: a living systematic review and network meta-analysis

    John G Lawrenson; Byki Huntjens; Gianni Virgili; Sueko Ng; Rohit Dhakal; Laura E Downie; Pavan K Verkicharla; Ashleigh Kernohan; Tianjing Li; Jeffrey J Walline

    10.1002/14651858.cd014758.pub3

    Cochrane 2025 indicates that pharmacological and optical interventions may reduce progression, but the certainty of results and long-term data are mixed.

    Last query 19.02.2024 . Does not include all tests with 2025–2026 ; poorly connected networks do not justify simple product ranking.

  20. 2024
    Official source Global N: not applicable / undetermined

    WHO SPECS 2030

    World Health Organization

    https://www.who.int/initiatives/specs-2030

    SPECS 2030 addresses access to refractive care more broadly; includes services, staff, education, costs and monitoring.

    It is not a myopia-only program and is not the source of the 49,8% projection.

  21. 2024
    Official Source Taiwan N: not applicable/undetermined

    MOHW — aktywność na zewnątrz i zdrowie wzroku dzieci

    Ministry of Health and Welfare, Taiwan

    https://www.mohw.gov.tw/cp-2704-79374-1.html

    Taiwan's official materials promote daily outdoor time and regular eye checkups for children.

    A public performance system has many components. Educational communication is not an evaluation of the causal effect of an entire policy.

  22. 2024
    Official source Singapore N: not applicable / not determined

    National Myopia Prevention Programme — odpowiedź MOH

    Ministry of Health, Singapore

    https://www.moh.gov.sg/newsroom/effectiveness-of-national-myopia-prevention-programme-s-strategies-for-primary-school-students/

    NMPP has been operational since 2001. MOH reported the myopia rate 26% in Primary 1 in 2023 and screening and education.

    Administrative data do not isolate the causal effect of a program; the result applies to Primary 1 , not to the entire population.

  23. 2024
    Systematic review Global N = 2380

    Safety of repeated low-level red-light therapy for myopia: A systematic review

    Yanping Chen; Ruilin Xiong; Shaopeng Yang; Ziyu Zhu; Huangdong Li; Kaidi Xiang; Nathan Congdon; Wei Wang; Mingguang He

    10.1016/j.apjo.2024.100124

    The RLRL safety review included 20 research; 1436 participants received therapy. No permanent vision loss was reported in the analyzed corpus.

    Median follow-up 9 months, maximum 24. Two descriptions referred to the same patient. The absence of an observed event does not prove zero risk.

  24. 2024
    Observational studyPolandN = 1049

    Artificial intelligence enhanced ophthalmological screening in children: insights from a cohort study in Lubelskie Voivodeship

    Regulski Piotr; Rejdak Robert; Niezgódka Marek; Iwański Michał

    10.1038/s41598-023-50665-5

    The publication regarding 1049 children from the Lublin Voivodeship reports 3,7% myopia.

    Narrow age and one region. The number of 1049 in the publication analysis is different from the administrative number of 1052 of pilot participants. We are not compiling them as an error or trend.

  25. 2024
    Guidelines / consensusEuropeN: not applicable / not established

    Myopia management algorithm. Annexe to the article titled Update and guidance on management of myopia. European Society of Ophthalmology in cooperation with International Myopia Institute

    Tapasztó B; Flitcroft DI; Aclimandos WA; Jonas JB; De Faber JHN; Nagy ZZ; Kestelyn PG; Januleviciene I; Grzybowski A; Vidinova CN; Guggenheim JA; Polling JR; Wolffsohn JS; Tideman JWL; Allen PM; Baraas RC; Saunders KJ; McCullough SJ; Gray LS; Wahl S; Smirnova IY; Formenti M; Radhakrishnan H; Resnikoff S; Németh J;

    10.1177/11206721231219532

    The ESO/IMI Complement organizes a pathway for risk assessment, intervention and control in the management of myopia.

    The algorithm supports the clinical decision; it does not replace examination and does not create a single regimen for all children.

  26. 2023
    Overview Global N = 1756

    Incidence of Corneal Adverse Events in Children Wearing Soft Contact Lenses

    Mark A. Bullimore; Kathryn Richdale

    10.1097/icl.0000000000000976

    A review of prospective studies of soft lenses in children estimated microbial keratitis at 2,7 per 10 000 patient-years.

    95% CI: 0,5–15 ; 3752 patient-years and one case. Wide uncertainty. We do not transfer this indicator to orthokeratology.

  27. 2023
    Case descriptionChinaN = 1

    Retinal Damage After Repeated Low-level Red-Light Laser Exposure

    Huanyu Liu; Yuan Yang; Jingli Guo; Jie Peng; Peiquan Zhao

    10.1001/jamaophthalmol.2023.1548

    Bilateral visual impairment and retinal changes have been reported following the use of RLRL; improvement was observed after exposure was discontinued.

    The case report is a safety signal, not an indicator of incidence or evidence that all devices have the same risk profile.

  28. 2023
    Observational studyPolandN = 1518

    Evaluation of the Prevalence of Refractive Defects and Ocular Function in a Group of 1518 Children Aged 8 Years in Northwestern Poland-A Retrospective Study

    Modrzejewska Monika; Magdalena Durajczyk

    10.3390/jcm12082880

    In a retrospective 1518 study of eight-year-olds, myopia was found in 16,8% subjects.

    Data from the years 2017–2019 ; publication 2023 . A regional sample, not a nationwide indicator and not another point in the series of Czepita's research.

  29. 2023
    RCTUSAN = 187

    Low-Dose 0.01% Atropine Eye Drops vs Placebo for Myopia Control: A Randomized Clinical Trial

    Michael X. Repka; Katherine K. Weise; Danielle L. Chandler; Rui Wu; B. Michele Melia; Ruth E. Manny; Lori Ann F. Kehler; Catherine O. Jordan; Aparna Raghuram; Allison I. Summers; Katherine A. Lee; David B. Petersen; S. A. Erzurum; Yi Pang; Phoebe D. Lenhart; Benjamin H. Ticho; Roy W. Beck; Raymond T. Kraker; Jonathan M. Holmes; Susan A. Cotter; ; Denise D. Alexopoulous; Megan Allen; Heather A. Anderson; Darrell S. Austin; Shane C. Black; Nicole M. Boyle; Grant Andrew Casey; Moriah Adine Chandler; Ryan Chinn; Deborah A. Clausius; Beth J, Colon; Courtney L. Conner; Linda T. Curtis; Zainab Dinani; Quayleen Donahue; Michelle Dubois; Patricia L. Evans; Brooke P. Fimbel; Melanie Kay Fowler; Richard P. Golden; Beth G. Harper; Robert J. Henderson; Dieu-Hong Ho; James E. Hoepner; Kristine B. Hopkins; Ashli S. Jenks; Joseph D. Kaplon; Shabana Khan; Cassandra A. Koutnik; Annie F. Kuo; Jessy Lee; Muriel M. Martinez; Sophia M. Marusic; Mary Lou McGregor; J. Ryan McMurtrey; Kathryn B. Miller; Preeti L. Mokka; Jenifer Montejo; Beth A. Morrell; Elyse Nylin; Kimberly C. Odom; Gillaine Ortiz; Samantha A. Parra; Kyle J. Perkins; Larry W. Plum; Ellen Fiona Redenbo; Julianne L. Robinson; Kathleen M. Stutz; Desirae R. Sutherland; Mircea X. Teodorescu; Lori L. Torgensen; David O. Toro; Phillip B. Turner; Natalie C. Weil; Emily K. Wiecek; Carsyn S. Wilkins; Victoria C. Woodard; Kevin M. Woodruff; Huizi Yin; Marika L. Yumang; Tomohiko Yamada; Noha S. Ekdawi; David A. Leske; David K. Wallace; Melanie L. Christian; Stephen R. Glaser; Eileen E. Birch; Angela M. Chen; Stephen P. Christiansen; Laura B. Enyedi; Donald F. Everett; Sharon F. Freedman; William V. Good; Erin C. Jenewein; Richard London; Vivian M. Manh; David G. Morrison; Stacy L. Pineles; Hantamalala Ralay Ranaivo; Tawna L. Roberts; Scott T. Ruark; Bonita R. Schweinler; Jayne L. Silver; Donny W. Suh; Lisa C. Verderber; Marie Diener-West; John D. Baker; Barry Davis; Rosemary D. Higgins; Stephen W. Poff; Richard A. Saunders; Lawrence Tychsen

    10.1001/jamaophthalmol.2023.2855

    In the American PEDIG RCT, atropine 0,01% did not slow progression or axis prolongation relative to placebo.

    The result relates to the tested concentration, preparation and population. It does not disprove the effects of all concentrations of atropine.

  30. 2022
    Observation by RCTChinaN = 114

    Sustained and rebound effect of repeated low-level red-light therapy on myopia control: A 2-year post-trial follow-up study

    Ruilin Xiong; Zhuoting Zhu; Yu Jiang; Xiangbin Kong; Jian Zhang; Wei Wang; Katerina Kiburg; Yixiong Yuan; Yanping Chen; Shiran Zhang; Meng Xuan; Junwen Zeng; Ian G. Morgan; Mingguang He

    10.1111/ceo.14149

    Follow-up of RLRL showed maintenance of the effect in those continuing and rebound in some people after discontinuation.

    Second year without re-randomization; only 11 children continued RLRL, 114 with 199 eligible were analyzed. It does not establish verified tapering.

  31. 2022
    RCTChinaN = 264

    Effect of Repeated Low-Level Red-Light Therapy for Myopia Control in Children: A Multicenter Randomized Controlled Trial

    Yu Jiang; Zhuoting Zhu; Xingping Tan; Xiangbin Kong; Hui Zhong; Jian Zhang; Ruilin Xiong; Yixiong Yuan; Junwen Zeng; Ian G. Morgan; Mingguang He

    10.1016/j.ophtha.2021.11.023

    In the multicenter RCT RLRL, the mean adjusted axis gain at 1 year was 0,13 mm versus 0,38 mm in the control group.

    No sham; annual observation, Chinese population. We do not transfer the result to any red light lamps.

  32. 2022
    Official source Poland N: not applicable / undetermined

    Podsumowanie pilotażu „Dobrze widzieć”

    Public institution identified in the source

    https://www.gov.pl/web/edukacja/wyniki-jednoznacznie-wskazuja-ze-program-musi-byc-kontynuowany--minister-przemyslaw-czarnek-podsumowal-wyniki-pilotazowego-programu-dobrze-widziec

    In 2022, the Ministry of National Education summarized the "Good to See" pilot: 1052 covered children from 10 schools.

    The administrative scope of the program is not an estimate of the incidence throughout Poland.

  33. 2022
    RCTChinaN = 170

    Spectacle Lenses With Aspherical Lenslets for Myopia Control vs Single-Vision Spectacle Lenses: A Randomized Clinical Trial

    Jinhua Bao; Yingying Huang; Xue Li; Adeline Yang; Fengchao Zhou; Junqian Wu; Chu Wang; Yuhao Li; Ee Woon Lim; Daniel P. Spiegel; Björn Drobe; Hao Chen

    10.1001/jamaophthalmol.2022.0401

    Testing of spectacle lenses with aspherical microlenses showed inhibition of progression for the HAL design compared to single vision lenses.

    Product and design-dependent result; is not a direct comparison of HAL with DIMS.

  34. 2021
    Stress conferencesPolishN: nie dotyczy / nieustalone

    Ocena wpływu aktywności fizycznej na stan narządu wzroku – aktualny stan wiedzy

    Ewa Grudzińska; Monika Modrzejewska

    https://ppm.edu.pl/info/article/PUM3fc0b3d9c80a4a4181aaf5f71bc1d5c6/

    Polish conference report on physical activity and the organ of vision. PPM/PUM record: 2021, p. 191–192.

    The bibliographic record was verified, not the full text of the abstract. We do not attribute a numerical effect or randomized trial level of evidence to this item.

  35. 2021
    Official source Poland N: not applicable / undetermined

    Dobrze widzieć — uruchomienie pilotażu

    Public institution identified in the source

    https://www.gov.pl/web/edukacja/dobrze-widziec--program-profilaktyki-krotkowzrocznosci-u-uczniow-z-edukacji-wczesnoszkolnej

    The pilot project “Dobrze widzieć” received PLN 1,1 million in funding and covered children in the Lublin Voivodeship.

    The announcement and budget of the pilot do not demonstrate the implementation of a sustainable national program.

  36. 2021
    Guidelines / consensusEuropeN: not applicable / not established

    Update and guidance on management of myopia. European Society of Ophthalmology in cooperation with International Myopia Institute

    János Németh; Beáta Tapasztó; Wagih A Aclimandos; Philippe Kestelyn; Jost B Jonas; Jan-Tjeerd H N De Faber; Ingrida Januleviciene; Andrzej Grzybowski; Zoltán Zsolt Nagy; Olavi Pärssinen; Jeremy A Guggenheim; Peter M Allen; Rigmor C Baraas; Kathryn J Saunders; Daniel Ian Flitcroft; Lyle S Gray; Jan Roelof Polling; Annechien EG Haarman; J Willem L Tideman; James Stuart Wolffsohn; Siegfried Wahl; Jeroen A Mulder; Irina Yurievna Smirnova; Marino Formenti; Hema Radhakrishnan; Serge Resnikoff

    10.1177/1120672121998960

    ESO and IMI present a framework for the selection of management, prevention and monitoring of myopia progression.

    The guidelines require reference to current knowledge, local availability and the specific patient.

  37. 2020
    Meta-analysisGloballyN: not applicable/undetermined

    The Complications of Myopia: A Review and Meta-Analysis

    Annechien E. G. Haarman; Clair A. Enthoven; J. Willem L. Tideman; Milly S. Tedja; Virginie J. M. Verhoeven; Caroline C. W. Klaver

    10.1167/iovs.61.4.49

    The severity of myopia is associated with higher odds ratios of maculopathy, retinal detachment and some other eye diseases.

    Data largely observational. The odds ratio (OR) is not the absolute risk of a particular child; definitions and reference groups vary between studies.

  38. 2020
    RCTHong KongN = 183

    Defocus Incorporated Multiple Segments (DIMS) spectacle lenses slow myopia progression: a 2-year randomised clinical trial

    Carly Siu Yin Lam; Wing Chun Tang; Dennis Yan-yin Tse; Roger Pak Kin Lee; Rachel Ka Man Chun; Keigo Hasegawa; Hua Qi; Takashi Hatanaka; Chi Ho To

    10.1136/bjophthalmol-2018-313739

    In the DIMS RCT, the average axis extension over the 2 years was 0,21 mm compared to 0,55 mm with single vision lenses.

    Study of the specific design of DIMS ; 160 children completed follow-up. Online 2019, volume of 2020 magazine. It does not prove that all defocus glasses work.

  39. 2019
    RCTGloballyN = 144

    A 3-year Randomized Clinical Trial of MiSight Lenses for Myopia Control

    Paul Chamberlain; Sofia C. Peixoto‐de‐Matos; Nicola S. Logan; Cheryl Ngo; Deborah Jones; Graeme Young

    10.1097/opx.0000000000001410

    The three-year MiSight RCT showed slower refractive error and ocular axis growth with daily disposable dual-focus lenses tested.

    Examination of a specific lens; 109 of 144 participants are three years old. It is not proof for every soft lens.

  40. 2019
    RCTHong KongN = 438

    Low-Concentration Atropine for Myopia Progression (LAMP) Study: A Randomized, Double-Blinded, Placebo-Controlled Trial of 0.05%, 0.025%, and 0.01% Atropine Eye Drops in Myopia Control

    Jason C. Yam; Yuning Jiang; Shu Min Tang; Antony K.P. Law; Joyce J. Chan; Emily Wong; Simon T. Ko; Alvin L. Young; Clement C. Tham; Li Jia Chen; Chi Pui Pang

    10.1016/j.ophtha.2018.05.029

    In LAMP, atropine 0,05% provided greater control of refraction and axis extension than 0,025% and 0,01% in the first year of the study.

    The response was concentration dependent; this result does not establish the optimal dose for each child.

  41. 2019
    Model/meta-analysisGloballyN: nie dotyczy / nieustalone

    Potential Lost Productivity Resulting from the Global Burden of Myopia: Systematic Review, Meta-analysis, and Modeling

    Kovin S. Naidoo; Timothy R. Fricke; Kevin D. Frick; Monica Jong; Thomas J. Naduvilath; Serge Resnikoff; Padmaja Sankaridurg

    10.1016/j.ophtha.2018.10.029

    Naidoo et al.'s model estimated the potential loss of productivity due to uncorrected myopia at 244 billion in 2015.

    95% CI: 49–697 USD billion. This is a model of lost productivity, not health care expenses or the cost of all refractive errors.

  42. 2019
    ConsensusGloballyN: nie dotyczy / nieustalone

    IMI - Defining and Classifying Myopia: A Proposed Set of Standards for Clinical and Epidemiologic Studies

    Daniel Ian Flitcroft; Mingguang He; Jost B. Jonas; Monica Jong; Kovin Naidoo; Kyoko Ohno-Matsui; Jugnoo Rahi; Serge Resnikoff; Susan Vitale; Lawrence Yannuzzi

    10.1167/iovs.18-25957

    IMI defines myopia as spherical equivalent ≤− 0,50 D and high myopia as ≤− 6,00 D with relaxed accommodation.

    Pathological myopia means structural changes; is not an automatic synonym for high defect. The high myopia threshold is different from Holden 2016.

  43. 2018
    Overview Poland N: not applicable / undetermined

    The review of refractive studies of nonadults in Poland

    Andrzej Grzybowski; Michal S. Nowak

    10.1111/aos.13666

    Grzybowski and Nowak compiled Polish refraction studies of minors, showing the diversity of data by age and examination.

    The review published in 2018 does not replace current representative national monitoring.

  44. 2018
    Observational studyPolandN: not applicable/undetermined

    Characteristics of Refractive Errors in a Population of Adults in the Central Region of Poland

    Michal Nowak; Piotr Jurowski; Andrzej Grzybowski; Janusz Smigielski

    10.3390/ijerph15010090

    Nowak, Jurowski, Grzybowski and Śmigielski described refractive errors in an adult population in central Poland.

    We do not transfer the results of adults to children. The regional trial is not a monitoring of the entire country.

  45. 2017
    Stress conferencesPolishN: nie dotyczy / nieustalone

    Ocena wpływu aktywności fizycznej na stan narządu wzroku – aktualny stan wiedzy

    Ewa Grudzińska; Monika Modrzejewska

    https://ppm.edu.pl/info/article/PUMf36f5d73d47a40a598417dd6849a80ba/

    Polish conference report on physical activity and the organ of vision. PPM/PUM record: 2017, p. 101.

    The bibliographic record was verified, not the full text of the abstract. We do not attribute a numerical effect or randomized trial level of evidence to this item.

  46. 2016
    Observational studyEuropeN = 15693

    Association of Axial Length With Risk of Uncorrectable Visual Impairment for Europeans With Myopia

    J. Willem L. Tideman; Margaretha C. C. Snabel; Milly S. Tedja; Gwyneth A. van Rijn; King T. Wong; Robert W. A. M. Kuijpers; Johannes R. Vingerling; Albert Hofman; Gabriëlle H. S. Buitendijk; Jan E. E. Keunen; Camiel J. F. Boon; Annette J. M. Geerards; Gregorius P. M. Luyten; Virginie J. M. Verhoeven; Caroline C. W. Klaver

    10.1001/jamaophthalmol.2016.4009

    A longer eye axis and greater myopia were associated with a greater risk of uncorrectable visual impairment.

    Extreme axle lengths are rare. A population association cannot be turned into an individual prognosis for a child.

  47. 2016
    Model / meta-analysisGloballyN = 2100000

    Global Prevalence of Myopia and High Myopia and Temporal Trends from 2000 through 2050

    Brien A. Holden; Timothy R. Fricke; David A. Wilson; Monica Jong; Kovin S. Naidoo; Padmaja Sankaridurg; Tien Y. Wong; Thomas J. Naduvilath; Serge Resnikoff

    10.1016/j.ophtha.2016.01.006

    Holden et al.'s model (2016) estimated 49,8% myopia in the world population in 2050. It is a projection, not a measurement of the future.

    145 research; extrapolating trends and replacing missing data with data from similar regions. 95% CI for 2050 : 43,4–55,7% . High myopia in this model: ≤− 5,00 D. The calculation was not made by WHO.

  48. 2015
    RCT clusterweChinaN = 1903

    Effect of Time Spent Outdoors at School on the Development of Myopia Among Children in China: A Randomized Clinical Trial

    Mingguang He; Fan Xiang; Yangfa Zeng; Jincheng Mai; Qianyun Chen; Jian Zhang; Wayne Smith; Kathryn Rose; Ian G. Morgan

    10.1001/jama.2015.10803

    Additional 40 minutes of outdoor activity on school days was associated with lower incidence in an RCT: 30,4% vs. 39,5% over 3 years.

    The primary outcome concerns the onset of myopia in children without it at baseline. It is not a measure of stopping existing progression.

  49. 2014
    Observation by RCTSingaporeN: nie dotyczy / nieustalone

    Atropine for the treatment of childhood myopia: changes after stopping atropine 0.01%, 0.1% and 0.5%

    Audrey Chia; Wei-Han Chua; Li Wen; Allan Fong; Yar Yen Goon; Donald Tan

    10.1016/j.ajo.2013.09.020

    After discontinuation of atropine in ATOM2, rebound dependent on the previous concentration was observed.

    The post-treatment phase concerns participants in a specific study. It does not designate a universal withdrawal pattern.

  50. 2012
    RCTHong KongN = 102

    Retardation of myopia in Orthokeratology (ROMIO) study: a 2-year randomized clinical trial

    Pauline Cho; Sin-Wan Cheung

    10.1167/iovs.12-10565

    In ROMIO, the average axis gain was 0,36 mm in orthokeratology and 0,63 mm in the single vision group over 2 years.

    78 children completed the study; unblinded users. Five people discontinued orthokeratology due to adverse events.

  51. 2012
    RCTSingaporeN = 400

    Atropine for the treatment of childhood myopia: safety and efficacy of 0.5%, 0.1%, and 0.01% doses (Atropine for the Treatment of Myopia 2)

    Audrey Chia; Wei-Han Chua; Yin-Bun Cheung; Wan-Ling Wong; Anushia Lingham; Allan Fong; Donald Tan

    10.1016/j.ophtha.2011.07.031

    ATOM2 compared the atropine concentrations of 0,5%, 0,1% and 0,01%; lower concentrations had a milder visual symptom profile.

    No parallel placebo arm. The historical placebo with ATOM1 is not an equivalent random comparator.

  52. 2007
    Badanie ObservationsPolishN = 4422

    Prevalence of myopia and hyperopia in a population of Polish schoolchildren

    Damian Czepita; Maria Żejmo; Artur Mojsa

    10.1111/j.1475-1313.2006.00419.x

    In the study by Czepita et al. published in 2007, myopia was diagnosed in 13,3% and 4422 students.

    Historical sample with a wide age range; does not describe the current incidence across the country.

  53. 2006
    RCTSingaporeN = 400

    Atropine for the treatment of childhood myopia

    Wei-Han Chua; Vivian Balakrishnan; Yiong-Huak Chan; Louis Tong; Yvonne Ling; Boon-Long Quah; Donald Tan

    10.1016/j.ophtha.2006.05.062

    ATOM showed slower refractive progression and ocular axis increase with atropine 1% than with placebo.

    One randomly selected eye was treated; Asian population. We do not transfer the effects and effectiveness of this concentration directly to low concentrations.

  54. 1971
    Historical studyUSAN: nie dotyczy / nieustalone

    The effect of atropine on myopia

    Bedrossian RH

    https://pubmed.ncbi.nlm.nih.gov/5163783/

    Bedrossian's record from 1971 documents the early stage of research on atropine in myopia.

    Verified metadata; no abstract in the register. We do not attribute the numerical effect or the contemporary standard of RCT. This is the oldest verified record for this version of the axis, not a claim of the first ever study.

  55. —
    Official source Poland N: not applicable / undetermined

    Prawo pacjenta do informacji

    Rzecznik Praw Pacjenta

    https://www.gov.pl/web/rpp/prawo-do-informacji

    The RPP describes the right to accessible information about proposed and possible methods and the foreseeable consequences of their use or omission.

    It does not imply an obligation to propose every existing method regardless of indications, evidence and availability.

  56. —
    Official source Poland N: not applicable / undetermined

    Pielęgniarka szkolna — profilaktyka i testy

    Public institution identified in the source

    https://pacjent.gov.pl/artykul/pielegniarka-szkolna

    School prevention includes, among others: visual acuity, strabismus and color vision test.

    A positive screening test requires further evaluation. Acuity screening is not a diagnosis of myopia or a national refraction registry.

  57. —
    Official source Hong Kong N: not applicable / undetermined

    Student Health Service — zakres świadczeń

    Department of Health, Hong Kong

    https://www.studenthealth.gov.hk/english/aboutus/aboutus_shscsac/aboutus_shscsac.html

    Student Health Service has been operating since 1995; an annual health assessment covers vision and referrals for follow-up care.

    A broad student health program, not just a myopia program.

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