Meta-analysis RCT2026

Efficacy and safety of low-concentration atropine combined with orthokeratology for children with myopia: a systematic review and meta-analysis of randomized controlled trials

Xue-Qian Zhang; Ming Chen; Xi Duan; Ya-Nan Shao; Le-Huan Chen; Shi-Yu Liu; Xiao-Xue Zhan

BMC ophthalmology

What does this source bring?

A meta-analysis of RCTs showed additional inhibition of axis lengthening for low atropine with orthokeratology compared to orthokeratology alone.

Differences in observation times and protocols; collective benefit does not imply indication for every combination.

CLAIM-AOK-META

Scope of testing and verification

The role of the record
Source of the claim
Population
Children with myopia; 11 RCT
N
Not applicable / not determined within the verified range
Geography
Globally
Observation (months)
Not applicable / not determined within the verified range
Comparator
Orthokeratology itself
Result
A meta-analysis of RCTs showed additional inhibition of axis lengthening for low atropine with orthokeratology compared to orthokeratology alone.
Safety
This record does not allow estimation of the frequency of rare adverse events.
Device/structure
Not applicable / not determined within the verified range
Publisher of the publication
Springer Science and Business Media LLC
Financing
Not determined within the proven range; see the declaration in full text.
Conflicts of interest
Not determined within the proven range. The absence of confirmation does not mean the absence of conflict.
DOI
10.1186 /s12886- 026-04816-7
PMID
42001024
What was checked
Bibliographic metadata and abstract in Europe PMC / PubMed; Crossref metadata
Date of verification
2026-09-09

This is the editorial card of the publication. The description does not replace the full text, supplementary data or instructions for a specific device.

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