RCT 2006

Atropine for the treatment of childhood myopia

Wei-Han Chua; Vivian Balakrishnan; Yiong-Huak Chan; Louis Tong; Yvonne Ling; Boon-Long Quah; Donald Tan

Ophthalmology

What does this source bring?

ATOM showed slower refractive progression and ocular axis increase with atropine 1% than with placebo.

One randomly selected eye was treated; Asian population. We do not transfer the effects and effectiveness of this concentration directly to low concentrations.

CLAIM-ATOM

Scope of testing and verification

The role of the record
Source of the claim
Population
6–12 children with myopia, Singapore
N
400
Geography
Singapore
Observation (months)
24
Comparator
Placebo
Result
ATOM showed slower refractive progression and ocular axis increase with atropine 1% than with placebo.
Safety
Mydriasis and decreased accommodation require clinical consideration.
Device/structure
Not applicable / not determined within the verified range
Publisher of the publication
Elsevier BV
Financing
National Medical Research Council (Crossref metadata; may not include all forms of support).
Conflicts of interest
Not determined within the proven range. The absence of confirmation does not mean the absence of conflict.
DOI
10.1016 /j.ophtha. 2006.05.062
PMID
16996612
What was checked
Bibliographic metadata and abstract in Europe PMC / PubMed; Crossref metadata
Date of verification
2026-09-09

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SOURCE RECORD

Source record