RCT 2019

Low-Concentration Atropine for Myopia Progression (LAMP) Study: A Randomized, Double-Blinded, Placebo-Controlled Trial of 0.05%, 0.025%, and 0.01% Atropine Eye Drops in Myopia Control

Jason C. Yam; Yuning Jiang; Shu Min Tang; Antony K.P. Law; Joyce J. Chan; Emily Wong; Simon T. Ko; Alvin L. Young; Clement C. Tham; Li Jia Chen; Chi Pui Pang

Ophthalmology

What does this source bring?

In LAMP, atropine 0,05% provided greater control of refraction and axis extension than 0,025% and 0,01% in the first year of the study.

The response was concentration dependent; this result does not establish the optimal dose for each child.

CLAIM-LAMP

Scope of testing and verification

The role of the record
Source of the claim
Population
Children 4–12 years old, Hong Kong
N
438
Geography
Hong Kong
Observation (months)
12
Comparator
0,05%, 0,025%, 0,01% and placebo
Result
In LAMP, atropine 0,05% provided greater control of refraction and axis extension than 0,025% and 0,01% in the first year of the study.
Safety
Pupil, accommodation, acuity and quality of life were monitored.
Device/structure
Not applicable / not determined within the verified range
Publisher of the publication
Elsevier BV
Financing
Not determined within the proven range; see the declaration in full text.
Conflicts of interest
Not determined within the proven range. The absence of confirmation does not mean the absence of conflict.
DOI
10.1016/j.ophtha.2018.05.029
PMID
30514630
What was checked
Bibliographic metadata and abstract in Europe PMC / PubMed; Crossref metadata
Date of verification
2026-09-09

This is the editorial card of the publication. The description does not replace the full text, supplementary data or instructions for a specific device.

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