Cross-sectional study 2026

Safety analysis of repeated low-level red light therapy on cone mosaic and microvasculature by adaptive optics scanning laser ophthalmoscopy

Yu Yue; Ni Zhang; Ke-Yu Liu; Yuan-Yuan Zhong; Han Wang; Shu-Lin Liu; Wen-Juan Wan; Yan-Lai Zhang; Wen-Li Deng

Photodiagnosis and photodynamic therapy

What does this source bring?

The AOSLO study showed no significant loss of cone density or differences in microcirculatory parameters tested after at least 8 months of RLRL.

66 eyes, of which 20 in the RLRL group; the unit is the eye, not the number of patients. Cross-sectional examination does not exclude rare or distant lesions.

CLAIM-RLRL-AOSLO

Scope of testing and verification

The role of the record
Source of the claim
Population
Eyes of people with treated and untreated myopia and without myopia
N
66
Geography
China
Observation (months)
8
Comparator
Untreated myopia and eyes without myopia
Result
The AOSLO study showed no significant loss of cone density or differences in microcirculatory parameters tested after at least 8 months of RLRL.
Safety
The morphology of cones and the parameters of small vessels were assessed.
Device/structure
650 nm, 0,29 mW laser; the model needs to be checked in full text.
Publisher of the publication
Elsevier BV
Financing
Not determined within the proven range; see the declaration in full text.
Conflicts of interest
Not determined within the proven range. The absence of confirmation does not mean the absence of conflict.
DOI
10.1016/j.pdpdt.2026.105473
PMID
41974297
What was checked
Bibliographic metadata and abstract in Europe PMC / PubMed
Date of verification
2026-09-09

This is the editorial card of the publication. The description does not replace the full text, supplementary data or instructions for a specific device.

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