Soft contact lenses.

Separate evidence for specific structures

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What is this method?

Myopia control research includes dual-focus soft lenses and selected multifocal designs. A regular corrective single vision lens is not automatically a progression-suppressing intervention.

Mechanism and idea

The design combines vision correction with an additional defocus signal. MiSight and the lenses tested in BLINK are different interventions, with different solutions and parameters.

How has the evidence developed?

MiSight was evaluated in a multicenter RCT, and BLINK compared various additions to single vision lenses. We do not combine them in a fictitious, directly comparative study.

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Key randomized trials

2019RCTGlobal

A 3-year Randomized Clinical Trial of MiSight Lenses for Myopia Control

The three-year MiSight RCT showed slower refractive error and ocular axis growth with daily disposable dual-focus lenses tested.

Examination of a specific lens; 109 of 144 participants are three years old. It is not proof for every soft lens.

Publication, Authors and Restrictions

Evidence reviews and syntheses

The review is not a substitute for checking a specific intervention. The publication date and query end date may vary.

2023 Overview Global

Incidence of Corneal Adverse Events in Children Wearing Soft Contact Lenses

A review of prospective studies of soft lenses in children estimated microbial keratitis at 2,7 per 10 000 patient-years.

95% CI: 0,5–15 ; 3752 patient-years and one case. Wide uncertainty. We do not transfer this indicator to orthokeratology.

Publication, Authors and Restrictions
2025 Review/Consensus Global

IMI-Interventions for Controlling Myopia Onset and Progression 2025

IMI 2025 organizes optical, pharmacological, environmental and lighting strategies and the state of research on their effects.

Mature technologies and emerging methods have a different evidence base. The inspection is not an individual clinical eligibility assessment of the child.

Publication, Authors and Restrictions

What do longer observations tell us?

Both key RCTs in the registry span three years. Post-RCT extensions and follow-up wear answer further questions, but do not automatically represent further years of the same randomized comparison.

Safety

Lenses require clean hands, proper use and avoidance of contact with water. Microbial keratitis is rare but potentially serious. Prospective pediatric data indicate a low rate of such events under the wearing conditions studied.

Limitations and open questions

We do not transfer the risk of soft lenses to night orthokeratology. Progression percentages from different studies are not a common scale for product effectiveness.

  • Which lens design suits the refractive error and conditions of use?
  • How long does the effect last after lens wear is stopped?
  • Can the family consistently maintain hygiene and attend follow-up visits?

When is it considered?

They may be considered when the child and caregiver are ready for the rules of use and the examination allows for the selection of a lens. Eligibility is not determined by age alone or the power of the glasses alone.

What should be monitored?

  • Lens fitting, the cornea and the ocular surface
  • Hygiene, symptoms, regularity of wearing
  • Refraction and axis length gain

This is a framework for a conversation with a specialist, not an individual treatment plan.

References for this chapter

2021Guidelines/consensusEurope

Update and guidance on management of myopia. European Society of Ophthalmology in cooperation with International Myopia Institute

ESO and IMI present a framework for the selection of management, prevention and monitoring of myopia progression.

The guidelines require reference to current knowledge, local availability and the specific patient.

Publication, Authors and Restrictions

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