Night lens, day correction
Orthokeratology uses carefully selected rigid lenses worn during sleep to temporarily change the shape of the anterior surface of the cornea. The effect on the rate of eye axis elongation was also examined.
Changing the corneal profile corrects vision and changes the peripheral optical stimulus. The refractive effect is reversible; a shorter need to wear glasses during the day does not mean reversal of structural myopia.
ROMIO is one of the key RCTs. Current literature also includes combinations with low atropine concentrations and more recent studies of other combinations.
Go to full timelineIn ROMIO, the average axis gain was 0,36 mm in orthokeratology and 0,63 mm in the single vision group over 2 years.
78 children completed the study; unblinded users. Five people discontinued orthokeratology due to adverse events.
Publication, Authors and RestrictionsA Spanish RCT showed greater axis control when RLRL was added to orthokeratology than with orthokeratology alone.
Small, single-center and unblinded trial. This is a combination treatment study, not a European monotherapy RCT RLRL .
Publication, Authors and RestrictionsThe review is not a substitute for checking a specific intervention. The publication date and query end date may vary.
IMI 2025 organizes optical, pharmacological, environmental and lighting strategies and the state of research on their effects.
Mature technologies and emerging methods have a different evidence base. The inspection is not an individual clinical eligibility assessment of the child.
Publication, Authors and RestrictionsROMIO provides a two-year comparison. Further decisions require inspection of the axis and cornea, also after discontinuation of wearing. Changing topography is not a substitute for measuring eye growth.
Nightwear requires strict hygiene, proper care and regular assessment of the cornea. Contact with water and improper handling increase the risk of infection. We do not use soft lens data to calculate the risk of orthokeratology.
In ROMIO, some children did not complete the trial and five discontinued wearing due to adverse events. An RCT of this size does not accurately measure rare severe infections.
It is sometimes considered after assessing the cornea, the defect, hygienic conditions and the possibility of inspection. The family's willingness to care for the lens is part of the clinical eligibility assessment.
This is a framework for a conversation with a specialist, not an individual treatment plan.
A meta-analysis of RCTs showed additional inhibition of axis extension for low atropine with orthokeratology compared to orthokeratology alone.
Differences in observation times and protocols; collective benefit does not imply indication for every combination.
Publication, Authors and RestrictionsESO and IMI present a framework for the selection of management, prevention and monitoring of myopia progression.
The guidelines require reference to current knowledge, local availability and the specific patient.
Publication, Authors and Restrictions